Back to Vaccinations. Antibodies are proteins that recognise and fight off germs, such as viruses, that have invaded your blood. If you’re exposed to the flu virus after you have had the flu vaccine, your immune system will recognise the virus and immediately produce antibodies to fight it. It may take 10 to 14 days for your immunity to build up fully after you have had the flu vaccine. You need to have a flu vaccination every year as the antibodies that protect you from flu decline over time, and flu strains can also change from year to year. In February each year, the World Health Organization WHO assesses the strains of flu virus that are most likely to be circulating in the northern hemisphere over the following winter. Based on this assessment, WHO recommends which flu strains the vaccines should contain for the forthcoming winter. Flu vaccines protect against 3 or 4 types of flu virus usually 2 A types and 1 or 2 B types. Vaccine manufacturers produce flu vaccines based on WHO’s recommendations.
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